Who Is The First Person With Aids and HIV
Who Is The First Person With Aids and HIV
Where does HIV come from for some of us who remember the sudden emergence of HIV into the popular culture and awareness of the US?
After over 25 years of research and discovery that we can finally start to say with some confidence where HIV came from.
HIV is a Lentivirus on the basis of its genome and life cycle it's not all that unusual for the lentiviruses.
It infects immune cells primarily cd4 positive T cells and macrophages the other lentiviruses pursue. Similar, if slightly different life cycles there are linty viruses that infect cats goats horses sheep cows and monkeys.
Origin of AIDS and HIV
If you take a rhesus macaque a monkey from Asia and infect it with the SIV from the African monkey or if you infect the African monkey with the Asian virus the result is called simian AIDS.
“HIV has not been a human virus for very long if it was a virus with a lot of history with humans”
It was here that a colony of chimpanzees was found with a close relative of the ancestral strain of HIV based on mutation and divergence rates.
We can place at least one transfer of virus from chimp to a human at or around 1931 in the country now known as the Democratic Republic of Congo.
There is some evidence to suggest that previous transfers of a chimp to human may have occurred as far back as the 1880s but it's not yet clear.
Many were no doubt lonely and isolated in this new cultural setting it could be said that it was not African culture that led to the spread of HIV but the effect of colonialism and industrialization in an area that had frequent contact with our close primate relatives previous zoonotic transfers of HIV.
Two Groups of HIV
HIV into two main groups the HIV-1 and HIV-2 species the closest relative according to sequence variations for the HIV-1.
Africa possesses far more of the subgroupings of HIV than any other continent Europe and North America are dominated by a very narrow range of viral types the group M subtype B this is suggestive but not confirmatory of an African origin for the parent strains.
We know that SIV and HIV are both spread in the same ways sex and blood transfers blood-to-blood exposures.
However are 900 times more likely to result in infection than sex contact it's therefore likely that the transmission from primate to human called a zoonotic event.
Who Die First Due to AIDS & HIV
In the January, the first case was in Philippines named “Gaëtan Dugas” die due to AIDS related disease. He was Canadian citizen and flight attendant.
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